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My sister's keeper is a 2009 american drama film directed by nick cassavetes and starring cameron diaz, abigail breslin, sofia vassilieva, jason patric, and. “my sister's keeper” is a movie where one child, anna, is conceived solely so the director, nick cassavetes, plays out an honest story that. My sister's keeper (pg-13) warner bros (106 min) directed by nick cassavetes with cameron diaz, abigail breslin, alec baldwin.